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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Universities join hands in developing literacy tests
2010-03-19

 
At the signing ceremony, from the left, are: Prof. Driekie Hay (Vice-Rector: Teaching and Learning), Prof. Albert Weideman (Head: Department of English) and Prof. Lucius Botes (Dean: Faculty of the Humanities).
Photo: Supplied


The development of academic literacy tests recently took a step into the future with the formal establishment of the Inter-institutional Centre for Language Development and Assessment (ICELDA).

ICELDA, under its first executive head, Prof. Albert Weideman, Head of the Department of English at the University of the Free State (UFS), is a cooperative venture between the multilingual Universities of Pretoria, North-West, Stellenbosch and the Free State.

It is dedicated to the development of reliable state-of-the-art academic literacy tests and currently makes 32 000 tests available to partnering universities annually.

Most notably, it has produced three of the most reliable academic literacy tests in the country. These include an Academic Listening Test and the Test of Academic Literacy Levels (TALL) for undergraduate students, with reliability levels that are more than 20% above international benchmarks.

“We are even more excited about our Test of Academic Literacy for Postgraduate Students (TALPS), which is already a crucial instrument in determining the literacy levels of postgraduate students at the Universities of the Free State, Pretoria and North-West,” said Prof. Weideman.

In addition, ICELDA is currently piloting studies for language tests for financial advisors, nurses, students of disaster management, as well as police studies at Unisa.

ICELDA will also collaborate with the Centre for English Language Communication (CELC) at the National University of Singapore.

“One of the undertakings I made on my visit to Singapore a year ago was that I would assist in every way I could with the building of joint expertise with CELC in language testing,” said Prof. Weideman.

“However, our focus will remain firmly on research.”

He said his goal was to employ the surpluses generated by selling tests to provide promising students with bursaries to stimulate further study and design of academic literacy and other language tests.

By drawing more researchers into the field, Weideman said, ICELDA could provide the capacity for developing reliable language tests that South Africa had always lacked.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
19 March 2010
 

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