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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS Qwaqwa student off to the USA
2010-03-29

Ayanda Xaba.
Photo: Supplied
Ayanda Xaba, a second-year student from the Department of Political Science of the University of the Free State’s (UFS) Qwaqwa Campus, has been selected as a participant in the Africa English Language Study Programme. The programme is organised by the United States Embassy in Pretoria and 30 candidates from all over Africa have been selected for a training programme of two months in the USA.

Ayanda shall be an incumbent at the University of Delaware (UD) from 21 June-18 August 2010. The programme focuses on language acquisition, leadership skills building and civic education and engagement. The UD programme will include a cultural component that comprises excursions and meetings with civic organisations, journalists, local, state and federal officials that focus on government, media, and other relevant topics.

Although English language acquisition is the main focus of this exchange, grantees will also participate in a leadership seminar and complete a hands-on service project (student-led, staff-supported) in which grantees will volunteer in a niche area that has applicability in their home countries. As a part of this project, participants will develop an action plan outlining steps to initiate and implement a project appropriate to their home community. In order to increase the likelihood of implementation of the project upon their return home, relevant UD staff will provide follow-on online support, trouble-shooting, and monitoring after their departure from campus.

Ayanda has selected to be involved in a programme on Career Guidance for university students. She hopes to implement the training on the Qwaqwa Campus upon her return.

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