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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS academic joins an elite league of achievers
2010-04-14

Prof. Dingie van Rensburg, Director of the Centre for Health Systems Research  Development at the University of the Free State
Prof. Dingie van Rensburg
Prof. Dingie van Rensburg, Director of the Centre for Health Systems Research & Development at the University of the Free State (UFS), has joined an elite list of a only few distinguished individuals who have been awarded honorary doctorates by the University of Antwerp (UA) in Belgium.

He is only the third South African to be honoured in this way by the UA, following in the footsteps of Constitutional Court Judge Albie Sachs (2000) and former State President, Nelson Mandela (2004).

He is the first social scientist from South Africa to receive this honorary doctorate from the UA – the highest academic distinction of that university. The university has previously only awarded three honorary doctorates to social scientists: Prof. Raymond Boudon, sociologist at the University of Paris-Sorbonne (1995); Prof. Robert Putman, political scientist at Harvard University (2000); and Prof. John Nash (of A Beautiful Mind fame), mathematician and economist at Massachusetts Institute of Technology (MIT) and Princeton.

The award ceremony will take place on 29 April 2010 in Antwerp.

Prof. Van Rensburg has authored, co-authored and was editor of many books/volumes, chapters in books, monographs, research reports and articles in scientific journals. He has also presented and co-presented at numerous national and international conferences; and supervised a significant number of master’s, doctoral and post-doctoral students.

In his 17 years as director of the Centre he has initiated, managed and led approximately 50 research and development projects, several of them large and long-term projects, and many of an inter-institutional and multidisciplinary nature.

In 2002 he became an NRF-rated researcher and in 2007 his rating as an established researcher was renewed. In the past two decades he received several research grants simultaneously from both the National Research Foundation and the Medical Research Foundation of South Africa, mostly for projects on Tuberculosis, HIV/Aids and antiretroviral treatment.

Prof Van Rensburg holds membership of both the Suid-Afrikaanse Akademie vir Wetenskap en Kuns and the Academy for Science of South Africa; he also served for varying periods on the Councils of both these academies. He was also a member of various health bodies of the Free State Province and the National Science and Technology Forum.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
14 April 2010
 

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