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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS strengthens EU cooperation
2010-04-22

 
Seen here are, from the left: Prof. Ezekiel Moraka, Prof. Alain Verschoren, Rector of the University of Antwerp (UA), Prof. Aldo Stroebel, and Prof. Luc D’Haese, UA Presidential Steering Committee on Internationalisation, and UFS International Advisory Board Member. 
Photo: supplied

Prof. Ezekiel Moraka, Vice-Rector: External Relations, visited a number of institutions in Europe to strengthen collaboration and joint research activities. He was accompanied by Prof. Aldo Stroebel, Director: International Affairs. The Universities of Leuven and Ghent, both of which the UFS have longstanding and active agreements with, and both prominent research institutions, expressed their interest to expand and further support areas of collaboration in a number of disciplines.

The University of Antwerp, with whom the UFS has partnered in the pending Erasmus Mundus mobility partnership programme of the EU, was one of the main universities visited in the context of the Strategic Academic Clusters, long-standing collaboration in the areas of public health research and linguistics, and the exploration of international research funding opportunities.

Prof. Moraka was a special guest at the Going Global Conference in London hosted by the British Council in the session on Autonomy and Accountability: Achieving a balance between the needs of the State and tertiary education institutions. In addition, successful collaborative discussions were held at the Association for Commonwealth Universities (ACU) with Dr John Tarrant, Secretary-General, on funding opportunities for staff development and mobility support.
 

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