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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Authentic leaders inspire themselves
2010-04-30

 

 Dr Renalde Huysamen and Mrs Marietjie du Plessis.

Leadership is held in very high esteem. In today’s world the ability to lead and motivate yourself and others is of the utmost importance. This year, Dr Renalde Huysamen and Marietjie du Plessis from the Centre for Higher Education Studies and Development (CHESD) at the University of the Free State (UFS), continue to build on a year-long Leadership-Learning Community Programme that they launched last year.

The aim of the project is, amongst others, to assist academic and non-academic staff at the university not only to discover their own strengths as leaders, but also to dream about it in order to achieve lively, sustainable and flourishing communities of collaborative learning and development. During the first six months of the programme staff members of the UFS investigate their personal and professional experiences and in the process they grow as individuals and authentic leaders.

The group is very diverse in terms of race, gender, language and qualifications. According to Mrs Du Plessis this diversity creates an opportunity where participants learn to understand themselves and others better. Firm ties are forged in a supportive, safe and stimulating environment in which mutual learning can take place.

During the last six months of the year the focus is on research outputs for academic staff en projects for non-academic staff. Some personnel have already published articles and managed to build international relations by means of this. Non-academic personnel have engaged in projects to improve provision of service with great success.

The Leadership Programme comprises 40 hours and includes breakaway sessions, group and individual activities, interviews and conversations, out-door activities, narrations and research methodology. The sessions take place on the UFS campus, but two breakaway sessions at resorts near Bloemfontein are also undertaken. Although this programme has been launched in the Higher-Education sector, it can also be adapted to fulfil the needs of any other sector, says Dr Huysamen.

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