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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

King Letsie III wishes Moshoeshoe project every success
2004-10-14



King Letsie III of Lesotho attaches great importance to the Moshoeshoe project of the University of the Free State (UFS) and wishes it every success.

This was the message of King Letsie III to the audience that attended the première of the documentary on King Moshoeshoe, the founder of the Basotho nation, at the UFS last night ( Wednesday 13 October 2004).

The message was read on his behalf by Lesotho’s Minister of Communications, Science and Technology, Dr Mamphono Khaketla.

Dr Khaketla said that through this important initiative the UFS is sending an important message that the current and future leadership can learn useful lessons from past great leaders such as King Moshoeshoe.

She said the screening of the documentary on King Moshoeshoe was a joyous occasion where the leadership attributes of a great Basotho King, who lived more than two hundred years ago, have been captured on film.

“The initiative which has brought us together, demonstrates the importance which the University of the Free State attaches to leadership, particularly in our southern African region,” she said.

Dignitaries in the audience included the Lesotho Minister for Communications, Science and Technology, Dr Mamphono Khaketla, Queen Mopeli, the MEC for Education, Ouma Tsopo, the MEC for Safety and Liaison, Tate Makgoe, the Director General of the Free State, Dr Khotso de Wee, the Senior Private Secretary to King Letsie III, Mr Mabotse Lerotholi, the Vice-chancellor of the National University of Lesotho, Dr Mothibe, Acting Principal Secretary in the Ministry of Tourism, Environment and Culture, Mr Jobo Molapo, Chairman of the Council of the University of the Free State, Judge Faan Hancke, and Rector and Vice-chancellor of the University of the Free State, Prof. Frederick Fourie.

The documentary on the life and legacy of King Moshoeshoe was commissioned by the UFS as part of its Centenary year. It was produced by journalist Max du Preez and it will be screened on SABC 2 on Thursday 4 November 2004.
 

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