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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS appoints top academic
2010-05-13

 
Prof. Kwandiwe Kondlo


The University of the Free State (UFS) has acquired the services of a well-known political analyst, Prof. Kwandiwe Kondlo, as a Senior Professor in the university’s Centre for Africa Studies (CAS).

Prof. Kondlo, who worked for the Human Sciences Research Council (HSRC) prior to this permanent appointment, is an accomplished researcher and a well-heeled scholar in issues of transitional democracies, governance and social justice.

“I joined this university particularly because of its difficult history and what I have observed to be a sincere orientation to transform,” he said.

“I think that under the leadership of Prof. Jonathan Jansen (Rector and Vice-Chancellor of the UFS) and his team we are going to see a very interesting rebirth of the University of the Free State. And some of us who believe in ideas of reconciliation in negotiated democracies as part of nation formation actually feel we should throw the best we have into the transformation process and support this great guy.”

“I see my appointment as part of the excellence aspect of the transformation journey because the UFS, even though it does good work in certain areas, is not highly rated in terms of academic excellence and publications. That is why I was glad to be appointed to make a humble contribution,” he said.

“I think it is going to be useful to the UFS to have more people of high academic standing because the idea to improve scholarship is very central and of course shifts the focus to scholarly discourse. Let scholarly excellence reclaim the centre of the debate as the leadership deal with legacy issues and genuine transformation.”

“Let us see academics from this institution stand up to articulate key issues that are relevant to state formations and transformation in the country. Let us debate our role as academics in supporting the consolidation of our young democracy”

Prof. Kondlo sees his key role within the CAS as improving research output.

“In other words, I see myself as leading the way in the generation of journal articles, books and also national and international seminars,” he explained.

He said a lot of work still needed to be done, though, to profile the CAS nationally and on the continent as it was still a new initiative and thus relatively unknown.

“We will need to be very innovative in terms of research initiatives and identification of research associates in order to profile the work of the Centre,” he said.

“I think the UFS will claim its seat in the greater African academic family by virtue of the quality of its products. We do not want to re-invent the wheel; we want to come up with products that are unique and in that way help this university to claim its rightful position within the greater African academic family.”

Prof. Kondlo has also worked for, amongst others, the Department of Land Affairs, the National Prosecuting Authority and the South African Chamber of Commerce, as well as being involved with the Truth and Reconciliation Commission.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
13 May 2010
 

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