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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Ms Beatrice Marshoff praise documentary on the life and legacy of King Moshoeshoe
2004-10-14

The Premier of the Free State , Ms Beatrice Marshoff, has praised the University of the Free State for the initiative to produce a documentary on the life and legacy of King Moshoeshoe, the founder of the Basotho nation.

“The University of the Free State could not have chosen a better subject to celebrate its centenary. The life and legacy of King Moshoeshoe is indeed a befitting demonstration that this is Africa ’s century,” Ms Marshoff said in a statement.

The documentary called “The Renaissance King” was shown last night ( Wednesday 13 October 2004 ) for the first time at the UFS. It was commissioned by the UFS as part if its Centenary year and was produced by journalist Max du Preez.

“We wish to congratulate the producers and the university, for such a brilliant idea,” the premier said.

She called on other institutions to also get involved in nation-building projects such as this one.

“Your desire and intention as an institution to take up a new but deserved role in our social transformation agenda, is highly commendable,” Ms Marshoff said in her statement.

Because the premier had to attend to urgent government business she could not attend the function,but her statement was read on her behalf by the MEC for Arts, Sport and Culture, Mr Joe Mafereka.

Dignitaries in the appreciative audience included the Lesotho Minister for Communications, Science and Technology, Dr Mamphono Khaketla, Queen Mopeli, the MEC for Education, Ouma Tsopo, the MEC for Safety and Liaison, Tate Makgoe, the Director General of the Free State, Dr Khotso de Wee, the Senior Private Secretary to King Letsie III, Mr Mabotse Lerotholi, the Vice-chancellor of the National University of Lesotho, Dr Mothibe, Acting Principal Secretary in the Ministry of Tourism, Environment and Culture, Mr Jobo Molapo, Chairman of the Council of the University of the Free State, Judge Faan Hancke, Rector and Vice-chancellor of the University of the Free State, prof. Frederick Fourie.

The documentary on the life and legacy of King Moshoeshoe will be screened on SABC 2 on Thursday 4 November 2004 .

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