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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

High-level Texas delegation visits UFS
2010-08-13

Pictured here, from the left, back, are visitors from Texas and UFS management: Ms Stephanie Curs (Director: Office of the Vice President for Global Initiatives), Dr Edwin Price (Associate Vice-Chancellor for International Agriculture and Director of the Norman Borlaug Institute for International Agriculture), Dr Mike Greenwald (Professor and Program Director for the International Studies Program, College of Liberal Arts), Prof. Ward Wells (Professor and Associate Head for Professional Programs, College of Architecture, and Director of Academy for Visual and Performing Arts), Dr Glen Mills ( Professor and Head of Department of Architecture), and Dr Alan Sams (Executive Associate Dean, College of Agriculture and Life Sciences); front: Prof. Jonathan Jansen (Rector and Vice-Chancellor, UFS), Mr Eric Bost (former USA Ambassador to South Africa and Vice-President for Global Initiatives), and Prof. Ezekiel Moraka (Vice-Rector: External Relations, UFS). – Photo: Stephen Collett.

A high-level delegation from Texas A&M University in the USA, led by Mr Eric Bost, Vice-President Global Initiatives and previous USA Ambassador to South Africa, visited the University of the Free State (UFS) recently. The objective of the visit was to forge strategic linkages and research partnerships within the ambit of Texas A&M’s expanded Africa strategy.

Texas A&M has 50 000 students, and is internationally renowned and highly rated for its scholarship, academic achievement and excellent research profile. The delegation consisted of representatives from the President's Office, various deans and heads of departments.

The discussions during the visit identified a number of shared interests and common research foci, and colleagues were unanimous in their pursuit to strengthen the relations.

In January 2009 Mr Bost delivered his final official address as US Ambassador to South Africa on the UFS Main Campus. Mr Bost, a close friend of the UFS, has since sparked numerous activities to further the transformation agenda at the UFS, and is very supportive of the work of the International Institute for Race, Reconciliation and Social Justice. A number of Fulbright senior specialists from the US are participating in the further conceptualisation, roll-out and activities of the Institute.
 

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