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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS deserves right to decisions
2010-08-15

Following visits of various youth formations to the University of the Free State’s (UFS) Rector and Vice-Chancellor, as well as the Dean of Student Affairs the past week, the university sees the need to remind all stakeholders and outside organisations that, although their views and inputs may be welcomed, the university reserves the right to make decisions regarding student matters and protect our students against suspected influences.

This reminder follows a series of meetings with organisations such as amongst others the Afriforum Youth and the ANC Youth League and subsequent media releases by some of these organisations, which often do not reflect correctly the nature and content of the discussions.

“While we welcome engagement with any organisation serving a non-racial, non-sexist and democratic agenda and regularly invite civil society organisations to dialogue with and assist us in student matters, we reserve the right to decide how to best serve interest of our students,” said Mr Rudi Buys, Dean of Student Affairs at the UFS.

“In our attempt to construct a value-driven, ethically sound and mature student governance environment, we also expect of stakeholders to ensure they engage us maturely and ethically at all times,” Mr Buys said.

“We will guard against organisations that may, under a guise of civil society engagement, wish to continue dysfunctional party-political cultures that fuel divisions and racial tensions among our students. In such cases where organisations by their conduct may prove themselves to do exactly that, we will have no other option but to refuse them entry to campus and set limits to their engagement of our students,” Mr Buys warned.

Media Release
Issued by: Lacea Loader
Director: Strategic Communication (actg.)
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl@ufs.ac.za  
14 August 2010
 

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