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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsies still enjoy successful exchange opportunity
2010-08-25

 
Students Ian Botha, Lize Swart and SW Meintjies with Prof. Izak Groenewald (second from right) at the O.R. Tambo International Airport in Johannesburg upon the student’s recent departure to Virginia Tech. Photo: Supplied

More than a decade ago, the then Chairperson of Free State Agriculture, Piet Gous, in collaboration with the then Dean of the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS), Prof. Piet Wilke, started an exchange initiative which still makes a difference to students’ lives today.

Students at the university get the opportunity to go and study at the Virginia Polytechnic Institute and State University (Virginia Tech) in Blacksburg in the United States of America (USA) during the second semester. During the first semester the UFS then receive American students. Since its inception in 1998, 142 students have already participated in the exchange programme.

“It is not only about six months’ studies at an American university. It is about the expansion of horizons, the creation of new frames of reference and exposure to other cultures and customs in order to attain and experience more life capacity,” says Prof. Izak Groenewald, Director of the Centre for Sustainable Agriculture and Rural Development at the UFS. Prof. Groenewald has acted as coordinator of this student exchange programme since 1997.

According to Prof. Groenewald, the secret of the successful programme rests with the fact that Kovsies pay their tuition and accommodation fees at the UFS as if they were studying here. However, they enjoy the privileges at Virginia Tech. Similarly, the American students pay their corresponding fees at Virginia Tech and then enjoy the privileges offered by the UFS. 

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