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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Dr Malete elected Chairperson of PanSALB
2010-09-06

Dr. Elias Malete

The Principal of UFS’s Qwaqwa Campus, Dr Elias Malete, was recently elected Chairperson of the Pan South African Language Board (PanSALB) at the 62nd General Board Meeting held in Pretoria. He is taking over from Prof. Sihawukele Ngubane from the University of KwaZulu-Natal (UKZN).

PanSALB is a constitutional body tasked with promoting and creating conditions for the development and use of eleven official languages in South Africa, including the likes of German, Greek, Gujarati, Hindi, amongst others.

“Our mandate going forward is to complement the good work that was done by Prof. Ngubane. We are charged with the responsibility of maintaining quality, respect, honesty and accountability in order to realise our new vision of promoting and ensuring respect for all languages commonly used by South African communities, including the Khoi, Nama and San languages, as well as South African Sign Language,” said Dr Malete.

“Our main focus in the next twelve months of office will be the development of programmes which will support PanSALB’s three-year strategic plan. These programmes will focus on administrative matters to ensure prudent financial and effective corporate governance of PanSALB, as well as aligning our structures like national language bodies, national lexicographic units and provincial language committees with the new strategic plan. This alignment is crucial if we are to create conditions for the development of all languages, thus promoting multilingualism and ensuring respect for all South African languages,” said Dr Malete.

Meanwhile, Dr Malete was invited by the Athens Institute for Education and Research to present a paper at the 3rd Annual International Conference in Literature, Language and Linguistics in Athens, Greece. His paper, Negation of adjuncts in Sesotho, was well received by the international audience.
 

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