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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof. Jansen is a "charmer", say students
2010-09-14

Prof. Jansen with Transport personnel.
Prof. Jansen with a B.Ed. student, Nokubonga Mdlalose.
Prof Jansen with Mr Samuel Mensah.
Prof Jansen with Sibusiso Macu, Sindiswa Masango, Mbali Phakathi and Masebabatso Mofokeng.
Prof. Jansen with Ms Mtombeni (in a white coat )

CHARMING, DOWN TO EARTH, STREEWISE … these are some of the words staff and students on the Qwaqwa Campus used to describe our Rector and Vice-Chancellor, Prof. Jonathan Jansen during his recent courtesy visit to the campus.

Prof. Jansen easily mingled and joined in conversations like a person who was acquainted to the groups of friends that he spoke to. Topics ranged from “girlfriends and boyfriends, how easy or difficult that course was, this and that party”, and of course serious academic talk.

“Prof. Jansen jokingly asked me about my white coat and whether I was a medical doctor. And when I answered that I am a cleaners’ supervisor, he became more interested in what I had to tell him,’ said Ms Dineo Mtombeni, a Maintenance Services supervisor.

“He continued to praise me and my colleagues for the cleanliness on campus and I must say he showed that he is a caring person, despite his position,” concluded Ms Mtombeni.

“I was happy to see Prof. Jansen chatting informally with students and staff. I asked him what he thought of our campus and he said he would know it better once he started teaching here once or twice a week,” said Mr Samuel Mensah, Economics lecturer.

“I then invited him to present some Economics classes and he roared with laughter about the difficulty of dealing with our micro and macro aspects of the subject and I asked him to keep it down as that would justify my students’ fear of the subject,” laughed Mr Mensah.

“He is a nice and friendly person,” said a 19-year-old Bachelor of  Commerce student Masebabatso Mofokeng.

“We shared a joke or two with him and it was one of our best experiences here on campus,” added friends, Sindiswa Masango (19) and Mbali Phakathi (19), who are also studying for their Bachelor of Commerce degrees.

A Bachelor of Education student, Nokubonga Mdlalose (20) described Prof. Jansen as a ‘charmer’.

“He is generous with his time, despite the high position that he occupies. He is approachable, friendly, charming, cool, calm and collected,” said Nokubonga.

“He asked me about my studies and I told him I wanted to make a difference in as far as teaching science is concerned. He was very interested in my Biology experiments and I am so glad I met him,” concluded Nokubonga.

– Thabo Kessah

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