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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof. Johan Grobbelaar part of history
2010-09-23

Prof. Johan Grobbelaar from the Department of Plant Sciences at the recent 31st Congress of the International Limnological Society (SIL), which was held in Cape Town.
Photo: Supplied

The 31st Congress of the International Limnological Society (SIL) was recently held at the Cape Town International Convention Centre (CTICC).

Prof. Johan Grobbelaar from the Department of Plant Sciences at the University of the Free State (UFS), who is also the chairperson of the local organising committee (LOC), worked hard for six years to secure the bid to host the congress in South Africa. The LOC consisted of Prof. Grobbelaar, Prof. Brian Allanson, Prof. Jenny Day, Dr Carin van Ginkel and Dr Mike Silberbauer.

SIL was founded in 1922 to further the study and understanding of all aspects of limnology, the science of inland aquatic ecosystems and their management.

Congresses are held every three years and this was the first time that SIL met on the African continent.

Almost 400 delegates from 42 countries attended this congress where the state of the science of limnology was presented with two keynote speakers, six plenary lectures, 230 oral and 76 poster presentations, mostly running in five parallel sessions. Exhibitions displayed some of South Africa’s role players as well as the latest equipment from abroad. Delegates could also join pre- and post-congress excursions and the new SIL journal, Inland Waters, was launched at the congress.

Many of the presentations dealt with water as a limited resource, pollution problems and the impact of climate change. The congress resolved that SIL would play a more prominent role in creating awareness of problems impacting on inland waters and also afforded solutions. The 32nd SIL congress will be held in Budapest, Hungary in 2013.
 

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