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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

US Consul-General speaks at the UFS
2010-09-23

Mr Andy Passen, US Consul-General, and Mr Arthur Johnson from the Internationalisation Office at the UFS.
Photo: Leonie Bolleurs

The Consul-General of the United States of America, Mr Andy Passen, recently presented a public lecture at the University of the Free State (UFS). He focused on the importance of youth development in the current dispensation and introduced President Barack Obama's Young African Leaders Forum. In his presentation he pressed upon the young leaders that they possessed both the privilege and responsibility to shape the future of Africa for the next 50 years.

He also engaged the UFS as a potential host of the Brown vs Board of Education exhibition, namely Separate is not equal. The exhibition is hosted annually at various cities and higher education institutions in South Africa. The multimedia exhibition uses films, photographs, sound recordings and reconstructions to tell the history of segregation in the USA, the landmark supreme court ruling in Brown vs. Board of Education on 17 May 1954, and the subsequent decades of struggle for racial equality. The exhibition also highlights parallels to the South African experience.

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