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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Church Mirror 2010 kicks off from the Free State
2010-10-04

Prof. Kobus Schoeman

 Prof. Kobus Schoeman, Head of the Department of Practical Theology at the University of the Free State (UFS), is one of the project leaders of Church Mirror, a unique research project in the family of Dutch Reformed Churches in South Africa.

Over the years Church Mirror has been established as an important source of information for the Dutch Reformed Church. The church is provided with information by means of surveys that assist in reflection on the church as well as congregations’ role and functioning.

The 2010 survey will be no exception. The survey is conducted on the instruction of the General Synod and in collaboration with the Department of Practical Theology at the UFS. This year, the project is also extended to other churches in the Dutch Reformed Church family for the first time.

The questionnaire forms part of the National Church Life Survey, which is done internationally. The questionnaire is completed by everybody who attends a church service on a specific Sunday. Questions that are asked include, “What do the members of the congregation think of their congregation and church services?”, “Are outsiders welcome?” and “Do we care about the community?”

The first survey was done amongst churchgoers at a service in 2006.

Church Mirror is an important research project to outline the profile of mainstream churches in South Africa and it can play a major role in congregations’ planning and reflection upon themselves.
 

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