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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS Extraordinary Professor involved in public signing of historic charter
2010-10-27

Prof. Iain Benson

Prof. Iain Benson, an Extraordinary Professor in the Department of Constitutional Law and Philosophy of Law at the University of the Free State (UFS), was one of the speakers at the signing of the historic South African Charter of Religious Rights and Freedoms on Thursday, 21 October 2010.

Thursday’s signing of the charter was the culmination of two years’ work of the Continuation Committee responsible for drawing up the document, of which Prof. Benson is a part. All the major religions signed the charter at the ceremony Thursday where Prof. Benson was one of the four speakers, who included the Deputy Chief Justice of South Africa, Justice Moseneke.

The charter, which has already received considerable international and national attention, will now be submitted to the ANC government for negotiations. Indicative of the important role that Prof. Benson played in the process of drawing up the charter is that he has been offered a role as an advisor for the newly created committee responsible for the drafting of the Constitution of the Council of Religious Freedom.

Originally hailing from Canada and currently residing with his family in France, Prof. Benson is an academic with a wealth of experience and expertise in the field of law, especially with regard to right of conscience and religion. His achievements number many, including being a Senior Associate Counsel at one of Canada’s leading law firms, Miller Thompson LLP; and serving on the Founding Board of the Global Centre for Pluralism. Prof. Benson gave his inaugural lecture last week with a lecture entitled Living together with Disagreements and the Limits of the Law.

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