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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof. Van Coller elected as member of ASSAF
2010-11-08

Prof. Hennie van Coller

After he had been nominated by Prof. Jonathan Jansen, Rector and Vice-Chancellor of the University of the Free State (UFS), Prof. Hennie van Coller, Head of the Department of Afrikaans and Dutch, German and French, was elected as a member of the Academy of Science of South Africa (ASSAF).

ASSAF consists of approximately 340 members and Prof. Van Coller is proud to be the only Afrikaans literator amongst the members. Apart from Prof. Dingie Janse van Rensburg, who retired earlier this year, Prof. Van Coller is also the only staff member of the UFS’s Faculty of the Humanities who is a member of ASSAF.

Prof. Van Coller is a former Chairperson of the South African Academy for Science and Art and states that his membership of ASSAF proves that a good relationship and collaboration exist amongst the academies for the benefit of science.

The academy’s core function requires that the country’s most outstanding academics be honoured as members. With that in mind, Prof. Van Coller’s research and contribution to Afrikaans literature were not in vain. “Recognition cannot be bought, and therefore recognition by one’s peers in particular is very precious,” said Prof. Van Coller.
– Lize du Plessis

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