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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS forms International Advisory Council
2010-11-09

The University of the Free State (UFS) has established an International Advisory Council (IAC) to advise the leadership of the university on its future positioning strategies, especially in relation to its international ambitions as a place of scholarship and service among the leading universities in the world.

The Council, constituted by Prof. Jonathan Jansen, Rector and Vice-Chancellor of the UFS, consists of nine high-profile international experts with proven expertise, leadership, influence and experience.

“Since the appointment of Prof. Jansen, the leadership of the university has been revising and aligning several functions as part of a thrust to position the institution to meet 21st century national, regional and international challenges,” says Prof. Aldo Stroebel, Director of International Affairs at the UFS.

The appointment of the IAC is one of the strategies to advise and guide the UFS during the next phase of development and growth.

The university is fortunate to have attracted council members from various spheres of influence who can provide strategic guidance and bring cutting-edge expertise to bear on the policies, strategies and actions plans of the UFS. Among them are Prof. Brenda Gourley, former Vice-Chancellor of the University of Natal (now UKZN); Mr Gert Grobler, SA Ambassador to Japan; and Ms Phumzile Mlambo-Ncquka, Former Deputy-President of South Africa, and Executive Chairperson of the Umlambo Foundation.

The first meeting of the Council will take place from 10-13 November 2010. During this meeting the Council will advise the university leadership on the positioning of the UFS in a global knowledge economy; research excellence; excellence in the scholarship of teaching and learning; student engagement and transformation; and other strategic programmes of focus, including engaged scholarship.

The other Council members are:

- Prof. Joel Samoff: Professor of African Studies, Stanford University, USA (Chairperson)
- Prof Luc D’Haese: Chairperson: University International Committee and Advisor to the Rector, University of Antwerp, Belgium
- Prof. Masafumi Nagao: United Nations University and International Christian University, Japan
- Dr Uri Ofir: International Entrepreneur and Business Development Specialist, Scientech Inc., Switzerland
- Prof. Alice Pell: Vice-Provost International Affairs, Cornell University, USA
- Prof. Akilagpa Sawyerr: Former Secretary-General, Association of African Universities (AAU), Ghana

Media Release
Issued by: Lacea Loader
Director: Strategic Communication (actg)
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl@ufs.ac.za
8 November 2010

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