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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS academics work on text book about legal requirements for cultural institutions
2010-11-09

Prof. Johan Henning, Dean of the Faculty of Law, UFS; Prof. Loot Pretorius, also from the Faculty of Law; and Mr Tokkie Pretorius, Director of the War Museum in Bloemfontein.

A team consisting of Prof. Johan Henning, Dean of the Faculty of Law at the University of the Free State (UFS), Prof. Loot Pretorius, also from the Faculty of Law, and Mr Tokkie Pretorius, Director of the War Museum, is going to tackle a project which will focus on the new legal requirements for cultural institutions, with special reference to national museums.

Previously this team has written a textbook on the legal position of development corporations, which is regarded as a standard work about this topic.

Museum managers often come from the expert conservation and research environment and find it difficult to comply with the new legal requirements pertaining to national museums.

National museums, amongst which counts the War Museum of the Boer Republics, are classified by the Public Finance Management Act (PFMA) no. 1 of 1999 as Public Entities.

This Act also states specific accounting requirements regarding the accounting standards, year-end statements and the auditing process on the one hand, but on the other hand specific requirement with regard to corporate management.

The King II Report and it most recent extension, King III, sets specific guidelines to be followed in the managerial process and specifically emphasises the role and responsibilities of non-executive boards of directors (board members) and those of the executive director (chief executive officer). The Cultural Institutions Act, no. 119 of 1998, regulates the operation of national museums, amongst others the constitution and functions of the boards of national museums. Various other forms of legislation also apply to national museums.

According to Prof. Pretorius they aim to publish the book within the next 18 months.
 

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