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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Centre for Africa Studies launches its ANC Centenary Seminar Series
2010-12-10

Prof. Chris Landsberg, Dr Pule Matjoa, Prof. Kwandiwe Kondlo and Herbert Maserumule, the main speakers during the launch of the ANC Centenary Seminar Series.
Photo: Christiaan van der Merwe

The Centre for Africa Studies at the University of the Free State (UFS) recently launched its series of seminars commemorating the centenary celebrations of the African National Congress (ANC). The launch of the series took place on 30 November 2010, with the seminar series running from February 2011 until February 2012, the year of the centenary celebrations of the ANC.

Along with UFS staff members and students, various special guests also attended the launch of the seminar series, including former Premier Ms Winkie Direko, representatives of the office of the current Premier and the Vice-Chancellor and Rector of the UFS, Prof. Jonathan Jansen. Prof. Jansen praised the Centre for Africa Studies for its vision in establishing the seminar series and added that he would be a regular attendee when the seminars kicked off in 2011.

The seminar series is the brainchild of Prof. Kwandiwe Kondlo, Head of the Centre for Africa Studies at the UFS. Prof. Kondlo explained that the aims of the seminars were to delve into the legacy of the ANC from a firm historical perspective, as well as to develop a firmer understanding of the dynamics of contemporary South Africa. He stressed the scholarly and academic nature of the seminars, hoping for robust and critical debate amongst future audiences about the topics at hand. Publications in journals and books at the end of the series will be the secondary objective of the Centre.

The three guest lecturers for the launch were Dr Pule Matjoa, Prof. Chris Landsberg and Herbert Maserumule. Dr Matjoa, an ANC veteran, elucidated the history of the party from an insider’s perspective while Prof. Landsberg spoke about the past and present foreign policy of the ANC. Mr Maserumule examined the ruling party’s economic thinking, with special focus on the distinctions between a democratic and developmental state.

The question-and-answer session after the lecture produced lively debate, which set a premise for the rest of the series. The first seminar in the series will take place on 4 February 2011.
 

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