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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Two Rhodes scholars are doing the UFS proud
2010-12-09

 
Sannah Mokone and DW Bester

Sannah Mokone and DW Bester were selected as Rhodes Scholars for 2011. It is the first time that the UFS has two students who have been awarded this sought-after scholarship in the same year.

Sannah is currently completing her B.Pub.Hons degree at the UFS and will read for an M.Sc. in Africa Studies at Oxford.  DW is completing his honours degree in Actuarial Science and will read for a D.Phil.

The UFS is honoured to have not only one but two students who will join the ranks of past Rhodes Scholars such as Justice Edwin Cameron, Dr David Woods, Adv. Bram Fisher, Dr Loyiso Nongxa, Mr Isaac Shongwe and Mr Kumi Naidoo, who was recently appointed as the Executive Director of Greenpeace International.

The Rhodes Scholarships, arguably one of the most prestigious scholarships in the world, were founded in 1903 in the will of Cecil John Rhodes and cover the full costs of study at Oxford University.

While academic excellence is a pre-condition for consideration for the Rhodes Scholarship, these scholarships are unique in that Rhodes Scholars are outstanding young students who excel academically, but very importantly, demonstrate leadership, are committed to making a difference in the world, and have the energy to fulfil their ambitions.

In the Southern African region four scholarships are available for South African residents in general; as well as one for KwaZulu-Natal; and one each for the alumni of Diocesan College, Paul Roos Gymnasium, St Andrew’s College and the South African College Schools (SACS). There is a further scholarship available for residents of Botswana, Lesotho, Malawi, Namibia and Swaziland.  

DW and Sannah were each awarded one of the South Africa-at-large scholarships.

Media Release
9 December 2010
Issued by: Lacea Loader
Director: Strategic Communication (actg)
Tel: 051  401 2584
Cell: 083 645 2454
E-mail: news@ufs.ac.za 

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