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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS presents unique rally
2005-06-07

On Friday 10 June 2005, the University of the Free State (UFS) will present the Kovsie version of the Amazing Race in Bloemfontein.

The Amazing Rainbow Rally will be held in aid of children and babies with serious diseases in the Department of Pediatrics and Child Health in the Faculty of Health Sciences.

By raising the necessary funds, equipment can be acquired to meet the unique health care needs of these special patients.  It will also enable the UFS to maintain the high standards of education, training and research in this field.

 The Amazing Rainbow Rally will give some residents of Bloemfontein an opportunity to test their knowledge of the city, as well as their time management skills, communication skills, team work and even their relationships! 

About 12 corporate teams from among others Vodacom, Eskom, Medi-Clinic, Mimosa Mall and Nedbank and four university teams must follow a specific route with various checkpoints by car.  Here they will have to complete activities or solve clues before receiving their clue to the next checkpoint.  Teams will be traveling with cars branded with the logo of the company they represent.

The rally will start at 09:00 at the Rooiplein of the UFS and will again end on the campus where they will complete the last task.  The first team to complete this task is the winner of Bloemfontein’s first Amazing Rainbow Rally.

OFM’s breakfast team will do live crossings on the day to reveal how teams are doing.

The Department of Pediatrics and Child Health at the UFS serves children with special needs, in other words children who need intensive care, or who suffer from cancer, heart disease, neurological diseases and conditions, endocrinological diseases or gastro-enterological conditions.

The Department provides secondary health care to more than 250 000 children in the southern parts of the Free State, but is responsible for the tertiary care of about a million children in the Free State and Northern Cape, as well as some parts of the North-West province, the Eastern Cape and Lesotho.  The intensive care units at Universitas and Pelonomi Hospitals serve approximately 1 300 neonatal and 350 intensive care patients annually.  The pediatric cardiology unit admits almost 300 high care heart patients per year.  Approximately 13 000 out-patients visit these two hospitals every year.

MEDIA RELEASE

Issued by:  Lacea Loader
   Media Representative
   Tel:  (051) 401-2584
   Cell:  083 645 2454
   E-mail:  loaderl.stg@mail.uovs.ac.za

7 June 2005
 

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