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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS joined EduRoam project
2011-03-13

Photo: Gerda-Marié Viviers

The ICT Services of the UFS presented the recent conference of the Association of South African University Directors of Information Technology (ASAUDIT) on home turf. Here from the left are: Prof. Janse Tolmie, senior director of the UFS’s ICT Services, Mr Sakkie Janse van Rensburg, executive director of the University of Cape Town’s ICT services, Mr Louis Marais, deputy director of the UFS’s ICT services and Mr Christiaan Kühn of the Council for Scientific and Industrial Research (CSIR).

Travelling academics should soon gain access to free internet more easily. This is after three South African universities, of which the University of the Free State (UFS) is one, joined the EduRoam project. Several academics were briefed on this concept at the last conference of ASAUDIT (Association of South African University Directors of Information Technology) which was held in the CR Swart Auditorium on the Main Campus of the UFS. EduRoam, which is available worldwide at participating universities and airports, enables users to gain access to the internet via their home universities. Prof. Janse Tolmie, senior director of the UFS’s ICT services explains that, should a colleague sign in at an “EduRoam university” the staff member’s information would be verified at the UFS’s IT systems in order to determine the legitimacy of the EduRoam user. After this internet access would be granted. The UFS, University of Cape Town and Rhodes University are the first three universities that have taken on the EduRoam project. The Council for Scientific and Industrial Research (CSIR) also plays a central role in the project in South Africa. More information regarding the UFS’s utilisation of EduRoam will soon be announced.

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