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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

"May Month of Compassion" for UFS staff
2011-05-04

 

From the left: Louis van Wyk (Central Region, Events Coordinator of ER 24) and Prof. Gert van Zyl, Dean of the Faculty of Health Sciences
Photo: Gerda-Marie Viviers

The Health and Wellness Centre of our university has kick-started the “Action of Compassion” which is aimed at promoting physical health for staff members of our university. This initiative is done in collaboration with Medi-Clinic and Pathcare who will be offering medical screening tests from 3 May 2011 until 13  May 2011. This forms part of the “Wake up to your Wellness – Take Control” programme of the Health and Wellness Centre. The tests will be done at 27 stations across our Main Campus. On 16  May the Wellness Centre will be at the South Campus and the date for a visit at the Qwaqwa Campus is to be established later. “The reason why we are doing this, is to conduct a research on Staff Wellness, give the staff feedback on their health and to create a database using the information we receive, so we can evaluate the health of our staff members and have them view their own status over time and whether they are making the right wellness choices,” said Dr Annette Prins.

This is a once-a-year initiative. Last year an estimated 1 100 staff members participated. This year the Health and Wellness Centre hopes to increase the figures. The medical screenings will include services like blood pressure, weight, height and BMI which will be conducted by Medi-Clinic and the cholesterol and blood glucose screenings will be conducted by Pathcare.

 

4 May 2011

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