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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

School of Nursing receives a considerable grant
2011-06-01

Our School of Nursing once again became the proud recipient of a grant from the Atlantic Philanthropies, an international organization dedicated to “bringing about lasting changes in the lives of disadvantaged and vulnerable people”.

Atlantic Philanthropies granted millions of rands to South African nursing training institutions via University Based Nursing Education (UNEDSA), which will provide six recipient institutions the opportunity to transform nursing academic programmes in South Africa over a period of four years.

We recently received a R3 100 000 grant for the school to transform nursing scholarship and clinical practice. This is but the latest installment in a total grant of R16 million.

The School of Nursing, under the leadership of Prof. Anita van der Merwe, former Head of the School of Nursing, submitted a proposal to UNEDSA and was selected as one of the six recipients of the award. The school is now at the beginning of the third financial year of the project.

According to Dr Annali Fichardt from the School of Nursing, the school established a unique Virtual Health Teaching and Learning facility for training students in a non-threatening, simulated environment and to prepare nurses to be capable and to function optimally in the dynamic health-care environment. This provides opportunities for experimentation and sharing of integrated teaching and learning in nursing education.

The project helped establish a new unit for continuing professional development and research capacity development to serve practicing nurses and staff members of the School of Nursing. These initiatives will result in a fully transformed and accredited portfolio of programmes at undergraduate, post-basic and postgraduate levels to meet the needs of a range of health-care settings and learners.

The School of Nursing hopes to create an innovative teaching and learning environment that empowers students and professional nurses to become clinically excellent, able to practice independently in both resource-poor and technology-rich areas, and manage such complexities in an innovative way.

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