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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
UFS Doctors make History in South Africa
2011-07-14
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| New aortic valve |
Three members of our Faculty of Health Sciences made history by being the first to implant a special new aortic valve in South Africa.
In a combined effort, the Departments of Cardiology, Pediatric Cardiology and Cardiothoracic Surgery did the first Medtronic CoreValve implant in South Africa on a patient in Universitas Academic Hospital.
With the support of hospital management and the Medtronic company, Prof. Hennie Theron, Prof. Stephen Brown and Dr JP Theron of the Faculty of Health Sciences, with the assistance of Dr Jean-Claude Laborde, performed the operation early on Wednesday morning, 06 July 2011.
The advantage of this new valve is that it can be implanted percutaneously through a catheter from the groin. This eliminates the need for invasive surgery.
The valve is made from porcine pericardium (tissue derived from pigs) and is mounted on an expandable stent, which is threaded along an artery, until it reaches its desired position. Prof. Theron says the valve is especially useful in older patients who suffer from aortic valve disease and pose a high surgical risk. Furthermore, the use of this valve greatly reduces hospitalisation time, in comparison to traditional surgery.
“One patient already received an implant this morning and we hope to finish 2 more today,” Prof. Brown said, emphasizing the swiftness and efficiency of the new valve implanting process.
“It is a complex procedure, but this service can in future be offered to all patients in the public and private sectors of the Free State. It is heartwarming that the academic complex can take the lead in this modern, high-tech therapy.”
For more information on the procedure, please contact Prof. Theron at 051 4053428.