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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsie Extravaganza
2011-09-14

 

Once again, Kovsies will showcase its most talented students at the Sand du Plessis Theatre in the annual Kovsie Extravaganza on 21st and 22nd September 2011. With guest artists, Vusi ‘The Voice’ Mahlasela and Die Heuwels Fantasties, it promises to be a first-class production. Expect music styles as diverse as hip-hop and pantsula dancers, a student string quartet, jazz band, various vocal groups and the winners of the campus serenade competition.

While it will certainly be a night to remember, this year will also benefit a cause you will find hard to forget. R25 of every ticket sold will go towards the No Student Hungry campaign (NSH), currently feeding just over a hundred Kovsie students on a daily basis. This means that the donation from each ticket bought will effectively buy one student food for one day.

Hunger on the Kovsie campus is an invisible problem that few ever consider, yet it affects an estimated 10% of the 31 000 students at Kovsies. ‘The problem with hunger at a learning institution is that it hampers talent. A hungry person can never achieve their full potential,’ says Grace Jansen, patroness of NSH.

To help alleviate this situation, you can buy a ticket for R75 at the PACOFS ticket office and join us on the 21st or 22nd September at the Sand du Plessis Theatre. Not only will it be a great night out, but you'll be doing your bit to invest in talent. Watch the press over the next two weeks for more information on this initiative.

If you'd like to know more about this topic or to schedule an interview with Cornelia Faasen, please contact her on 051 401 2819 or e-mail faasenc@ufs.ac.za.

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