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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof. Aldo Stroebel serves on SAYAS
2011-09-23

 

Prof. Aldo Stroebel


Prof. Aldo Stroebel, from our university, has been elected as a Founding Member of the South African Young Academy of Science (SAYAS).
 
He is currently Associate Professor in the Centre for Sustainable Agriculture, Rural Development and Extension, as well as the Director of International Academic Programmes in the Office of the Vice-Chancellor at the university.
 
The Young Academy has as its objectives to represent young scientists in advising the government on science and technology policy and human resource development. In addition, they will prepare the SAYAS to join the Global Young Academy (GYA) to engage with high-level international bodies, including the World Economic Forum. Twenty Founding Members have been elected – ten new members will be elected annually to a maximum of 50.
 
Prof. Stroebel obtained his master’s degree at the University of Ghent, in Belgium, and a PhD at the UFS after a year of graduate coursework at Cornell University in the USA. He completed post-doctoral work at Wageningen University and Research Centre in The Netherlands, where he has been appointed as a Visiting Fellow to their recently-established Centre for Food Security and Sustainable Development. He has published widely, including more than 90 journal articles, book chapters and reports, and co-edited a book published by CTA Wageningen. He has supervised ten master's and doctoral students.  
 
He serves in various capacities: he is a member of the Research and Innovation Strategy Group of Higher Education South Africa (HESA), former member of the SANPAD Board, the President of the International Network of Research Management Societies (INORMS) Conference in 2010, and Vice-President of Research and President-elect of the Southern African Research and Innovation Management Association (SARIMA).
 
Prof. Stroebel has participated in a number of national and international conferences. He was a keynote speaker at the Society of Research Administrators (SRA) in Washington DC in the USA and at the Ministerial Conference on Higher Education in Agriculture in Uganda.
 
He has worked as a consultant and/or advisor for a number of international and multinational organisations, including the Food and Agricultural Organisation of the United Nations (FAO), the United States Agency for International Development (USAID), World Bank, Lux Development, and the World Conservation Union (IUCN), Switzerland.
  

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