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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Cultivating excellence and success through academics
2011-10-07

 

Unlocking potential. At the Golden Key South African Summit 2011 were, from the left: Dr Derek Swemmer, Registrar (UFS); Prof. Driekie Hay, Vice-Rector: Academic; Mr Ryk Neethling and Ms Charlene Gunter, Director: Golden Key International Honour Society, South Africa.
Photo: Phelekwa Mpono

More than 130 delegates are gathering for the Golden Key, South African Summit at the Bloemfontein Campus of the University of the Free State (UFS). Golden Key International Honour Society recognises academic excellence and uses knowledge to transform lives. It has 400 chapters in eight countries. Of South Africa’s 12 chapters, 11 were present at the summit.

Prof. Driekie Hay, Vice-Rector: Academic at the UFS, welcomed delegates from the respective chapters. She commended them for their perseverance and dedication to excel. “Your academic aspirations and commitment contribute to cultivating a culture of excellence. It will provide a better future for every South African citizen,” she said. Prof. Hay challenged delegates also to “act” by turning their knowledge into actions to advance not only themselves but also society. She also urged them to “discover” everything about themselves, their chosen disciplines, allies and oppositions. “Mostly, you must internalise the spirit of lifelong learning,” she said.

Mr Ryk Neethling, Olympic gold medallist and businessman, was the first keynote speaker. He took everyone through the steps that ultimately led to the moment of victory for him and his team. “We found a way to compete with heart and determination in the 2004 Olympic Games. We were prepared and we took everyone by surprise. “To achieve what one has set one’s mind to, we must dream big,” he said. “Play your part in the team and be confident. Remember that you are victors and not victims,” he urged. He further emphasised the importance of making one’s own luck and, most of all, never to give up.

Another speaker for the summit includes Ms Peggy-Sue Khumalo, former Miss South Africa. Dr Derek Swemmer, Registrar (UFS) will present a workshop on Strategic Action Planning.

This event is the first external lecture that is presented in the Metro’s found in the new Health Sciences Building on the Bloemfontein Campus of the UFS.
 

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