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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Willem Boshoff’s artwork placed on Bloemfontein Campus
2011-10-21

 
Students viewing the new artwork on our Bloemfontein Campus
Photo: Hannes Pieterse

There was great excitement last week when Willem Boshoff’s Thinking Stone sculpture arrived and was installed near our Main Building. The black granite stone, which was quarried at Boschpoort Granite in Belfast, Mpumalanga, weighs approximately 20 tons and took about a year to polish to give it its burnished quality.

On the surface of the stone are engravings that resemble the prehistoric rock engravings of the Driekopseiland rock art site close to Kimberley. Added to the engravings are sandblasted inscriptions in six languages of verses and well-known quotes that refer to the word “rock”.

Willem Boshoff is one of South African’s most established artists and his artworks are deeply involved in relationships and focused on bringing about conversation. Willem describes the Thinking Stone as being “a place for gathering and sharing ideas, as universities should be”. The sculpture is a huge investment for our university and will, for many years to come, inspire thought, dialogue and contemplation.

Willem Boshoff’s sculpture is, to date, the largest of fifteen artworks commissioned by the Sculpture-on-Campus Project and funded by the National Lottery Distribution Trust Fund.
 

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