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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Historic Global exchange summit for first-year students in 2012
2011-10-21

 
More than one hundred Kovsie first-year students travelled to universities in the USA and Europe in September 2011 to learn about issues such as diversity, leadership and citizenship. More students will travel to Asia in January 2012. Daniel King, Melissa Lucas, Jomari de Beer and Rito Madingana visited Ghent University in Belgium.
Photo: Anja Aucamp

Our University will present a global exchange partner summit next year with the 16 partner universities who took part in this year’s Leadership for Change Programme. This will be the first summit of its kind presented in South Africa bringing together first-year students from four continents and 17 countries. The summit will take place from 8 - 22 July 2012 on the Bloemfontein Campus.

The aim of the summit is for first-year students from all partner universities in the USA, Europe and Asia to visit our university and experience student life at a South African university. The students will be staying on campus and an intensive programme covering issues such as social justice, diversity, leadership and citizenship will be presented.

Mr Rudi Buys, Dean of Student Affairs at our university, says the summit will serve as an opportunity to detail further partnership agreements with a number of universities such as Binghamton State University, amongst others.

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