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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Students selected for prestigious Stanford Sophomore College
2012-04-04

 

From the left are: Elri Marais, Palesa Mafisa, Prof. Jonathan Jansen, Vice-Chancellor and Rector of the UFS, Goodwill Shelile and Foster Lubbe. Gabriela Schroder and Saeed Abdullah were absent when the photo was taken.
Photo: Hannes Pieterse
4 April 2012


As part of the University of the Free State’s (UFS) comprehensive suite of student leadership development programmes, a strategic partnership with Stanford University, USA has been forged.

Starting in 2012, selected cohorts of high-potential second-year students will annually participate in the Stanford Sophomore College Programme. The UFS and Oxford University in the UK are the only non-Stanford participants in this strategic and unique opportunity.

Following a highly competitive selection process based on both written and oral assessment, managed by the UFS Centre for Teaching and Learning and the Office of the Vice-Chancellor, the first group of six students was recently selected and will visit Stanford University from 1 – 14 September 2012.

The exclusive and high profile Sophomore College has been offered at the prestigious Stanford University on the West Coast of the US for a number of years. It takes the form of a residential summer programme for second-year students who participate and engage in intense academic exploration with peers and professors on a variety of innovative, multidisciplinary topics.

Depending on the course selected, students participate in a variety of intellectual and academic programmes, do research, work in labs, engage in readings of texts and develop presentation skills.

Some courses are held in part or entirely off campus. Advisory sessions to assist students in their preparation, academic orientation and intellectual development will be conducted prior to their departure to add value to the experience at Stanford.

The students will benefit from the programme in many ways, among others the intense academic exploration of topics with an eminent international scholar, immersion in and exploration of a field of interest, the opportunity to hone critical habits of mind, train to become a more engaged and entrepreneurial learners and collaborate and form relationships with friends and peers.
 

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