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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

We show our colours in support of autism awareness
2012-04-11

The Main Building on our Bloemfontein Campus will be illuminated in blue till the end of April to show support for autism awareness.
Photo: René-Jean van der Berg
12 April 2012

The Main Building on our Bloemfontein Campus will be illuminated in blue till the end of April to show our support for autism awareness, together with the rest of the world.

April is Autism Awareness Month and various iconic landmarks worldwide will be lit up in blue to honour those with autism.

Autism is one of only three conditions that are commemorated by the World Health Organisation.

Autism is a neurological condition that can be diagnosed in children as young as three years old. Worldwide one out of every 100 children is diagnosed within the autistic spectrum. This means that in South Africa a child is born with autism every hour and in the Free State some 400 children per year are born with the condition.

“Despite the high prevalence of autism in South Africa, South Africans know very little about it,” says Dr. David Griessel, an autism expert of the UFS’s Department of Paediatrics and Child Health. “Stories and films that attempt to portray autistic characters often create the wrong impression among the public concerning this complex illness. This distorts the reality since every child with autism is unique,” says Dr. Griessel.

He says it is important that all children with signs of autism are referred for evaluation as early intervention can prevent autism from further disrupting normal development.

Therapists and teachers who specialise in autism-specific treatment play an important role in this regard.

“However, there are no well-established services for toddlers in the Free State. Fortunately, there are classes developing in schools such as Lettie Fouché, Willem Postma and Pholoho, as well as in Kroonstad and Welkom. The Free State Autism Association has established a private school that offers a service to seven learners.”

For more information on autism in children or for information on special projects in the Free State, contact Dr. Griessel at +27(0)51 405 53177 or +27(0)51 405 3181.

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