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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Another award proves quality of Architecture
2012-04-13

Jurie Swart with Mrs Martie Bitzer, Head of the Department of Architecture.
Photo: Supplied
13 April 2012

 

The Department of Architecture can be proud of its students. Recently, Jurie Swart was honoured as regional winner of the Corobrik Architectural Student of the Year Award. He was also placed second nationally.

Jurie is an architect at the The Roodt Partnership in Bloemfontein.
 
Corobrik says in a media release: “Tomorrow’s architects set new standards at 25th Corobrik Architectural Student of the Year Awards. Achieving sustainable built environments with low impacts on the natural environment is becoming a universal goal. Energy usage in buildings is under the spotlight. Water-wise projects are most likely to get the go ahead. That is why an in-depth understanding of the environmental constraints and impacts of technologies on architectural solutions is becoming so important for students of architecture. It is the resolution of environmental issues that can be expected to drive architectural expression that will shape tomorrow’s buildings and the creation, extension and redevelopment of our towns and cities.”

Jurie Swart’s project, Borderline – mediated landscape, a Water Research Centre for the University of the Free State (Qwaqwa Campus), explores whether nature and architecture can amalgamate to become a hybrid solution in a vast landscape which has lost its reference to place and time.

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