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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Public Protector addresses large audience
2012-04-23

Adv. Madonsela condemns corruption and poor service delivery in South Africa.
20 April 2012

Audio of the lecture


Video of the lecture

Apartheid cannot be blamed for poor service delivery in the country - corruption should shoulder the blame. Eighteen years into democracy, South Africa still has a long way to go before it becomes the society it envisaged for itself.

“We are not there yet,” South Africa’s Public Protector, Adv. Thuli Madonsela, told a packed Wynand Mouton Theatre on the University of the Free State’s Bloemfontein Campus on Tuesday 17 April 2012. She delivered a public lecture on “Academic freedom and corruption in the context of secrecy laws”.

“Are we closer to becoming a society where values such as human dignity are sacrosanct, where freedom for everyone is the order of the day?” Adv. Madonsela asked the audience comprising students, academics and community members. She said corruption is the silent thief that steals the country’s constitutional dream, causing the poor to live undignified lives.

Adv. Madonsela appealed to students and academics to help retrieve the constitutional dream. In encouraging academic discourse on corruption, she said corruption is not only one person’s problem, but that of everybody. She told academics they could help develop the law and so help in the fight against corruption.

Adv. Madonsela, who spent most of Tuesday on the Bloemfontein Campus, met with senior management from the university as well as students earlier.

Her public lecture late on Tuesday afternoon had the Wynand Mouton Theatre bursting at the seams. Some members of the audience sat on the steps inside the theatre to hear the lecture.

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