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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Odeion School of Music prepares for Europe
2012-05-09

 

Travelling to Europe in July will be, from the left: Lebogang Ledwaba (21); Maja van Dyk (19); Kgaugelo Mpyane (22); Neo Phambuka; and Heinrich Lategan (18)
Photo: Hannes Pieterse
9 May 2012

Ten young musicians from the Odeion School of Music (OSM) will travel to Europe later this year after being selected as members of the 2012 Miagi Youth Symphony Orchestra.

These talented musicians will play at venues in Germany and Austria in July 2012. As part of the Miagi Youth Symphony Orchestra, they will share the stage with some of the best youth orchestras from around the world. On the orchestra’s itinerary is a performance at the Young Euro Classic Festival in Germany where they are scheduled to perform at the opening concert. The Young Euro Classic is the world’s premier festival for symphonic youth orchestras. Before their trip to Europe, the Miagi Youth Orchestra will play at a farewell concert at the Linder Auditorium in Johannesburg.

The Miagi Youth Orchestra operates under the auspices of a non-profit organisation MIAGI (Music Is A Great Investment). The organisation covers all costs of the European tour.

Ms Ingrid Hedlund, Creative Manager of Miagi, says 88 young musicians have been selected for the 2012 events and tour of Europe. She finds the level of talent of the students studying at the Odeion School of Music very high. That is why so many students from the OSM were selected to play in the orchestra.

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