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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Making a difference is the most important thing for Gary Kirsten
2012-05-16

 

Gary Kirsten
16 May 2012

“Can I make a difference in someone’s life?” This was the central driving force for Gary Kirsten, head coach of the 2011 World Cup winning Indian cricket team. He currently coaches the Proteas.

Gary was the first guest speaker at a new series of lectures at our Business School. Challenges and solutions in management will be highlighted in the series. In his lecture, Gary was interviewed by Prof. Johann Coetzee, Extraordinary Professor at the Business School. The audience got a glimpse of the person often seen on television screens and they travelled with him from his childhood days at the Newlands Cricket Ground to his days in New Delhi as head coach of the Indian team.

His challenge in India was to develop a new culture in a team with very valuable and expensive brands. His light-bulb moment occurred on a team-building visit to Australia. His question to the team was what he could do for them and what they would expect from him. The turning point was Sachin Tendulkar’s answer: I would like you to be my friend. Tendulkar’s wife’s comment on the winning night was the proof of his success. She said: “The last three years were the happiest in my husband’s life.”

Gary said it was an incredible privilege to make a difference in people’s lives. “I wake up asking myself where I can make a difference in someone’s life. You must create an environment for people to enjoy the game, challenge one another and thrive.”

He is confident that the Protea team has the potential to be a great cricket team. He said the upcoming England tour is a test. “This tour will test us to be the top team in the following years. I would like to set them up for the best chance to win.”

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