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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Three more Kovsie staff members involved in Olympic Games
2012-05-30

 

Dr Derik Coetzee
Photo: Supplied
30 May 2012

The South African men’s hockey team will practice on our Bloemfontein Campus from 28 May to 8 June 2012, and the team count on the assistance of three Kovsies to prepare them for the Olympic Games taking place in London later this year.  

Dr Derik Coetzee, senior lecturer in the Department of Exercise and Sport Science and Head of our High Performance Centre, has been appointed conditioning coach of the team. He will be assisted by Colleen Jones and Riaan Schoeman, also from this department.

The UFS team and Mr Gregg Clark, the team’s coach, will work out a periodisation programme for the team, which will continue until the hockey finals at the Olympic Games. The programme includes the correct exercises, volume, intensity and number of exercise sessions per week.

This is not the first time that Dr Coetzee has assisted sports teams to prepare for important events. In 2007, he was the conditioning coach of the Springbok rugby team that won the World Cup in France. He was also the conditioning coach of the under-21 Springbok team in 2002 that won the Junior World Cup Tournament. 

Dr Coetzee says it is a challenge to ensure that the team performs well at the Olympic Games. “The joy on the faces of the coach and players when they qualified in Japan cannot be described because many people thought they would not qualify.”

With the addition of Dr Coetzee, Ms Jones and Mr Schoeman, a total of six staff members from the UFS will be involved with the Olympic Games and the Paralympic Games. The other three are:

  • Dr Louis Holtzhausen, Head of the university’s Department of Sports and Exercise Medicine, has been selected as team doctor for the more than 300 athletes that will represent South Africa at this year’s Olympic Games (in London).
  • Ms Ebeth Grobbelaar, Assistant Director of the South African Testing Laboratory for Prohibited Substances at the UFS, was invited to be involved in the Drugs Control Centre in the unit against prohibited substances which will test sportsmen and -women during the games.
  • Ms Hetsie Veitch, Head of the Unit for Students with Disabilities, has been invited to be a member of the Classification Panel at the final USA Paralympic athletics trials.

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