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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS visits Namibian schools
2012-06-27

The Rector and Vice-Chancellor of the University of the Free State, Prof. Jonathan Jansen, will leave for Namibia shortly to visit several secondary schools in the country and to speak to students.

The visit will be from Monday 25 June to Friday 29 June 2012.

A group of other staff members from the UFS, including Mr Rudi Buys, Dean: Student Affairs, Prof. Lucius Botes, Dean of the Faculty of the Humanities and Prof. Neil Heideman of the UFS’ Faculty of Natural and Agricultural Sciences, will also be part of the visit.

Prof. Jansen’s visit to schools in Walvis Bay, Swakopmund, Windhoek and Rehoboth is aimed at reaching out to potential UFS students in Namibia.
Prof. Jansen’s visits to schools since 2010 were very successful and he decided to expand his visits to schools with other ambassadors of the UFS to Namibia.

There are currently a large number of Namibian students at the UFS and the UFS also boasts a significant Namibian Kovsie alumni.

During the UFS’ five-day-visit to Namibia, the group will visit the Walvis Bay Private High School, Namib High School, the High Schools of Jan Mohr, Dr Lemmer, M&k Gertze, Windhoek Gimnasium, MH Greeff, Technical High School as well as Windhoek High School.

On Wednesday 27 June, Prof. Jansen will address ex-Kovsies at an alumni reunion in Windhoek.

On Thursday 28 June, Prof. Jansen will speak to approximately 600 learners at the Davin Trust sports event and on Friday 29 June he will address about 150 business people at a business breakfast in Windhoek.
 

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