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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Read a book SA encourages South Africans to read one book a month
2012-09-20

Campus Principal Dr Elias Malete on the left and Tebogo Ditshego's. With them are Betsy Eister, UFS Director: Library and Information Services and Mathene Mahanke from the Department of Sport, Arts, Culture and Recreation.
20 September 2012

'Read a book SA's" objective is to bring reading into the everyday lives of South Africans. Speaking at Writers’ Day on the Qwaqwa Campus of the University of the Free State last Thursday, Ditshego said reading was essential. “Of all the skills that anyone can ever have, reading is the most fundamental of them all. It improves one's attention, confidence and discipline, amongst others.”

Ditshego asked why South Africa is presently faced with a 25,2% unemployment rate compared to Germany's 6-8%, despite South Africa having more and better natural resources. The answer, according to him, rests with lack of knowledge and critical skills in South Africans.

“Out of 144 countries, South Africa is ranked 133th in as far as the delivery of quality education is concerned. The reason for this is that South Africans lack knowledge, as they do not read enough. Most South Africans read for information, which is different from knowledge,” Ditshego argued.

In his welcoming remarks, Campus Principal Dr Elias Malete challenged authors to continue reminding society of their responsibilities.

“It is also your duty and responsibility to teach diplomacy lessons, to teach about effective leadership that is accountable, fair and transparent,” said Dr Malete.

Amongst the established authors who shared their wisdom with budding writers was Dr KPD Maphalla, a Sesotho literature guru and custodian of Sesotho language and culture. UFS students and learners from Sekgutlong and Tiisetsang secondary schools had the opportunity to showcase their writing skills. They also received expert advice on manuscript development and publishing from Mathene Mahanke from the Free State's Department of Sport, Arts, Culture and Recreation.

The annual Writers' Day is a joint venture of the Campus Principal and the Library and Information Services (LIS).

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