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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS confers honorary doctorate on one of the world’s foremost academics
2012-11-26

Prof. Martha Nussbaum
Photo: Supplied
26 November 2012

The University of the Free State (UFS) will confer three honorary doctorates at the Summer graduation ceremony on 6 December 2012. One of the world’s foremost philosophers is among those to be honoured. Prof. Martha Nussbaum, described by The New York Times as “one of the most prominent female philosophers in America”, will be honoured with a D.Litt. degree in the Faculty of Humanities. Judge F.D.J. Brand, a former Constitutional Court judge, and Prof. Otto Walter Prozesky, one of the country’s foremost medical researchers, will also receive honorary doctorates.

Prof. Nussbaum, who has honorary doctorates from 40 colleges and universities in America, Canada, Asia and Europe, is recognised for her intellectual and public contribution to human development. She is the Ernst Freund Distinguished Service Professor of Law and Ethics at the University of Chicago and an active member of the American Philosophy Association. Prof. Nussbaum is well-known and respected as a public intellectual and is considered to be one of the most prominent philosophers in the world.

Prof. Prozesky is to be honoured for the important role that he played in the field of medical research, especially as the President of the Medical Research Council and as researcher/educator in the field of virology and HIV/Aids. He is to receive an honorary degree in Medicine in the Faculty of Health Sciences.

Judge Brand, Extraordinary Professor in Private Law in the Faculty of Law at the UFS, is to receive a Doctor Legum degree in recognition of his considerable contribution to the legal science. More than 120 of his judgments are reported in South African legal reports. A review of recent South African legal journals (over the past five years) shows that reference is made to his judgments in at least 30 articles and case discussions.

The Summer graduation ceremony will be held in the Callie Human Centre on the Bloemfontein Campus and will take place in two ceremonies. At 10:15, master’s degrees and doctorates will be awarded, and at 15:15 qualifications will be awarded in a combined graduation ceremony of the Faculty of Health Sciences and the School of Open Learning.

  • Prof. Martha Nussbaum will lead a conversation with members of the public and the campus community on 7 December 2012. On 8 December 2012, she is the main speaker at the UFS’s conference on “Engaging the Other: Empathy and Breaking Transgenerational Cycles of Repetition” on the Bloemfontein Campus.

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