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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Faculty of Law bids farewell to Prof. Andries Raath
2012-11-27

Prof. Andries Raath and some of his colleagues during his farewell held in the Bobbert Room of the CR Swart Building. From the left are: Prof. Loot Pretorius, Dr Ilse Keevy, Prof. Andries Raath, Prof. Johan Henning and Prof. Gerhard Fick.
Photo: Christiaan van der Merwe
27 November 2012


The Faculty of Law had to bid farewell to another stalwart in Prof. Andries Raath last week. Prof. Raath retired after more than 30 years of service to the university.  Prof. Johan Henning, Dean of the Faculty of Law, described it as a day of “great personal sadness” due to the loss of a person who had made such a tremendous impact in the faculty, both at a personal and an academic level.

Prof. Raath was praised for his academic prowess and relationship with students who referred to him as a “real professor”, and doctoral students who often saw him as a father figure. For his part, the avid Anglo-Boer War buff thanked long-time as well as newer colleagues, whom he said had all left an imprint on him in some way or another.  He urged his former colleagues to maintain the “precious academic heritage” of the faculty, in which his personal career also had numerous highlights.

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