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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

International conference on breaking cycles of the past in societies affected by historical trauma presented from 5-8 December 2012
2012-11-28

Marguerite Barankitse from Burundi
28 November 2012

An interdisciplinary group of scholars, experts and practitioners from 24 countries around the world will gather at the University of the Free State (UFS) in Bloemfontein from 5 - 8 December 2012 for a conference on “Engaging the Other: Breaking Intergenerational Cycles of Repetition.”

The conference intends to open new avenues of inquiry into the trans-generational effects of trauma on communities that have experienced extreme violence.

One of the highlights of the conference is a presentation by Marguerite Barankitse, a survivor of the Rwandan genocide, on Thursday 6 December 2012. Marguerite has received several awards and distinctions for her work aimed at transforming the lives of Hutu and Tutsi children affected by war. Among these are the highly prestigious humanitarian prize, the Opus Prize, the UNESCO Prize, and the World's Children's Prize, also known as the ‘Nobel Prize’ for humanitarian work aimed at improving the lives of children and their chances of a better future.

On Saturday 8 December 2012 Prof. Martha Nussbaum, one of the world’s foremost philosophers, will deliver a keynote address on “Reconciliation: The political role of the Arts.” Prof. Nussbaum will receive a D.Litt. degree in the Faculty of Humanities from the UFS on 6 December 2012.

Other guests include Michael Lapsley, survivor of an apartheid bombing, Kimberlyn Leary, Associate Professor at Harvard Medical School,  Dr Jean Decety, Irving B. Harris Professor at the University of Chicago and Dr Katerina Fotopoulou from the Institute of Cognitive Neuroscience at the University College in London.

One of the conference events entitled “South Africans speak about the crisis of moral leadership: A public dialogue” will be open to the public and presented in the Centenary Complex on Friday 7 December 2012 from 18:00-19:30. Participants in the public dialogue include some of South Africa’s most thoughtful social commentators and a community activist: Barney Pityana (Professor and Rector, College of Transfiguration); Prince Mashele (Director: Centre for Politics and Research); Pierre de Vos (Professor of Law, University of Cape Town); and Faeza Meyer (Chairperson: Tafelsig Residents Unite).

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