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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Library opens new horizons for Bloemfontein-Oos School
2012-11-27

Storyteller Gcina Mhlophe is hugging a learner at the Bloemfontein-Oos Intermediary School.
Photo: Kaleidoscope Photography
27 November 2012

“The more that you read, the more things you will know. The more that you learn, the more places you'll go.” Dr Seuss says that in his book I Can Read with My Eyes Shut!

It is hoped that this will also be the experience of learners at the Bloemfontein-Oos Intermediary School where a library has been stocked and unveiled with our assistance. Bloemfontein-Oos is one of the schools that the UFS renovated in partnership with the Free State Department of Education.

The learners also had the rare opportunity to listen to a doyenne of South African storytellers Gcina Mhlophe. She is one of the best storytellers, writers, publishers, directors and international poet.

Tessa Ndlovo, coordinator of the UFS Schools Partnership Programme, said she thought it was important for the school to have a library in order to cultivate a culture of reading. She asked publishers and libraries to send books and in the process, more than 2 000 books were donated by the UFS-Sasol Library, staff and students. New books were sent by publishing houses.

The office of Prof. Jonathan Jansen, Vice-Chancellor and Rector, sponsored the renovation of the library by donating shelves.

Bloemfontein-Oos became the first school in the UFS’s Extreme Makeover intervention. Attention has been given to fencing, electrification, renovation and the bathrooms. Three truckloads of furniture were donated and more will follow in future. The Calculator Project (Project of Peace) was introduced to the school by students from the United States of America.

The library is part of the Culture of Reading Project.

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