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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Multimillion rand donation to boost UFS schools
2013-02-05

At the launch were Dr Cobus van Breda, Director of the Science-for-the- Future Unit at the UFS, Mr Makhetha Botsane from the Free State Department of Education Mrs. Elizna Prinsloo, Programme Manager of the Family Maths and Family Science project and Mr Graham McCulloch, Free State representative of the Ilima Trust.
Photo: Kelly Abrahams
05 February 2013

The University of the Free State’s UFS) Family Maths and Family Science project has received a R1 million sponsorship from Old Mutual for 2013. This is a three-year project whereby the university’s School of Open Learning aims to demystify mathematics and science in the early school years, as stated in their mission. The launching ceremony took place on 1 February 2013 at the UFS Campus.

The sponsorship was made available by Old Mutual, but will be managed by the project management group, Ilima Trust.

The UFS received R30 million altogether from Old Mutual for the use on various projects.

Except for the Family Maths and Family Science project, the Schools make over project and the Internet Broadcasting Programme will also benefit from this donation.

“Ilima has a hands-on relationship with different projects and is the public face for the FM & FS sponsorship,” said Mr Graham McCulloch, Ilima Trust representative for the Free State.

“Today is the first step on the long road to improving math and science in the country,” McCulloch said.

Dr Cobus van Breda, Director of the Science-for-the-Future Unit  says the Family Math and Family Science Project makes science and math accessible to children and their parents in the early years, with the aim of developing positive attitudes towards these often difficult school subject.

“This project aims to empower educators, parents and student educators by iving support and training in hands-on teaching methodologies.”

Learners, educators and parents from 18 schools in Thaba Nchu and Botshabelo will benefit from this project. Teachers will receive training at the UFS and then return to their community to train parents and to teach learners. Teachers will also receive activity material to use in classrooms.

“The selection of the 18 participating schools took place by identifying feeder schools of secondary schools from the UFS School Change Project, trying to create a whole-school development,” Van Breda said.

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