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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof. André Keet appointed to Ministerial Oversight Committee on Higher Education
2013-01-15

 

Prof. André Keet
Photo: Anja Aucamp
24 January 2013



Prof. André Keet, Director of the Institute for Reconciliation and Social Justice at the university, has been appointed as member of the Oversight Committee on the Transformation of South African Universities. He is one of seven committee members that were appointed by the Ministry of Higher Education and Training to monitor progress on transformation in public universities.

The committee will advise Dr Blade Nzimande, Minister of Higher Education and Training, on policy to combat racism, sexism and other forms of unfair discrimination in public higher education. The committee will also advise on the role of universities in promoting the development of a free, fair and non-discriminatory society beyond the world of the academia.

The senior leadership of the university has welcomed the appointment of Prof. Keet and said with his extensive experience as a former Commissioner on the Commission for Gender Equality and as the Director of the university's Institute for Reconciliation and Social Justice (which was formed as one of several initiatives taken by the senior leadership in the aftermath of the Reitz incident), Prof. Keet will be a valuable member of the committee.

"Prof. Keet has the experience and expertise to guard the autonomy and academic freedom of universities, thus avoiding this committee from becoming a political intervention in the affairs of the higher education sector," said Prof. Jonathan Jansen, Vice-Chancellor and Rector of the university.

Honoured to be elected on the committee, Prof. Keet said he is ready to serve the national interest in the transformation of South African universities. "The appointment is also a compliment to the university and to its exceptional experience in the process of transformation."

Prof. Keet will serve on the committee for a period of three years. The other members of the committee are Prof. Malegapuru Makgoba, who will serve as chairperson, Dr Mvuyo Tom, Ms Nazeema Mohamed, Ms Zingiswa Losi, Mr Joe Mpisi and Prof. Shirley Walters.

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