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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Learners to benefit from UFS Partnership for academic excellence
2013-02-21

 

Thokoana Makaota learners listening attentively during the launch of the partnership with the UFS.
Photo: Thabo Kessah
21 February 2013

The university’s quest for academic excellence in the education system paved the way for the Faculty of Education on the Qwaqwa Campus to enter into a mutually beneficial partnership with a local school, Thokoana Makaota Secondary.

This recently launched partnership will enable learners who are currently in grades 10-12 to attend supplementary classes on the campus.

“The aim of this partnership is to expose learners from the school to adequate tuition in subjects that are generally perceived as difficult. We want them to gain as much confidence as possible when tackling these subjects, therefore they will be using our well-equipped laboratories and classes”, said Dr Lekhooe Letsie, the Programme Coordinator.

“We will also benefit from this as our own final-year education students will act as tutors. This will help them gain confidence before they venture into the real job market next year,” Dr Letsie said.

Dr Letsie also revealed that the student-teachers will be closely monitored by their mentors to ensure maximum success.

The school’s Deputy Principal and UFS alumnus, Serame Sello, said that the school felt humbled by this gesture from the UFS.

“We are confident that this working relationship will yield very positive results for the school and enable us to improve on the 84% pass rate obtained in 2012,” Sello said.

“We did not do so well in the subjects that will be covered here. For instance, we obtained 43% and 61% in Physical Science and Mathematics respectively, but with this partnership we hope for improved results this year,” said Sello.

Other subjects to be covered include Geography, Life Sciences, Economics, and Accounting. The different grades will commute to and from campus on different afternoons.

 

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