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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

House Madelief turns over a new leaf
2013-02-15

 

The new year has come with a lot of changes for House Madelief. The residence, home to 179 female students, had a make-over which changed its inside appearance. The changes include new relaxation and meeting spaces, changes in decor, as well as renovations to the residence’ and visitors’ bathrooms.

Notable changes include four different spaces which each present a unique, but blending identity. When not in class, residents can make use of the little coffee corner, a conference room for quick meetings, a lounge and relaxation area. New paintings were also hung in the men’s gazellie, consisting of artworks painted by talented Madelief resident, Kondi Shikwambani. 

With new decor came a new theme. “A place we call home, our home, Madelief," says Diatile Mohlakane, Prime of the residence. "Madelief is a vibrant place of colour, which has postitive energy flowing throughout the house."

Rudi Buys, Dean of Student Affairs, congratulated Madelief on its new appearances. "We are immensely proud of Madelief and of both the Residence Head and the Residence Committee for achieving change, not only in terms of what the residence’s facilities offer Madeliefies, but also in the apparent sense of community among students which have become a proud reality. Madeliefies are now known as people who live with values which inspire all around them."

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