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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Hussein Solomon, an expert voice on Islam in Africa
2013-02-25

Prof Hussein Solomon
Photo: Supplied
25 February 2013

Prof Hussein Solomon, Senior Professor in the Department Political Studies and Governance, has been appointed Senior Research Associate of the Israeli think tank Research on Islam and Muslims in Africa (RIMA). 

Prof Solomon will give an expert voice on the topic of Islam in Africa, participating with other researchers in the network on political Islam and terrorism on the African continent. The centre is the only one in the world which solely deals with Islam and Muslims in Africa.

An expert on the topic of Islam on the continent, Prof Solomon says it’s an important focus area given the rise of Al Shabab in Somalia and its terrorist attacks across the world. He further mentions the rise of Al Qaeda in the Islamic Maghreb and other such groups operating in Northern Mali, prompting the recent French intervention, as well as the increasing incidence of terrorism in Nigeria perpetrated by the Islamist Boko Haram.  "If you want to save lives, then you need to understand how such movements originated and how they operate."

The academic says through RIMA and its global network, he will work with other researchers and engage in collaborative research projects on the same issue, allowing for the rapid cross-pollination of ideas. "For the University of the Free State, it once more underscores the fact that, with the information age, you do not have to be in the capital of the country to be globally relevant. Indeed, in recent years the University of the Free State has increasingly been seen as a global actor in the academic arena."

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